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Cerebral PlasticityNew Perspectives$
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Leo M. Chalupa, Nicoletta Berardi, Matteo Caleo, Lucia Galli-Resta, and Tommaso Pizzorusso

Print publication date: 2011

Print ISBN-13: 9780262015233

Published to MIT Press Scholarship Online: August 2013

DOI: 10.7551/mitpress/9780262015233.001.0001

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Neurophysiological Correlates of Cortical Plasticity in the Normal and Diseased Human Brain

Neurophysiological Correlates of Cortical Plasticity in the Normal and Diseased Human Brain

Chapter:
(p.291) 23 Neurophysiological Correlates of Cortical Plasticity in the Normal and Diseased Human Brain
Source:
Cerebral Plasticity
Author(s):

Rossini Paolo Maria

Melgari Jean-Marc

Publisher:
The MIT Press
DOI:10.7551/mitpress/9780262015233.003.0023

This chapter is concerned with the results of studies performed with neurophysiological techniques. Their integration with flow/metabolic methods constitutes, at present, the best way to evaluate plasticity in the normal and abnormal human brain as represented by three paradigmatic conditions: healthy aging, neurodegeneration, and ischemic stroke. It concentrates on neurophysiological correlates of cortical plasticity. This chapter shows that since, both in healthy aging and in different models of disease, neuroplasticity is an efficient way to maintain brain function despite progressive loss of its resources, deepening the knowledge on the mechanisms regulating cerebral function and plastic phenomena might prompt newer and more efficacious therapeutic and rehabilitative strategies for neurologic diseases.

Keywords:   cortical plasticity, healthy aging, neurodegeneration, ischemic stroke, neuroplasticity, brain function, human brain

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