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Single Neuron Studies of the Human BrainProbing Cognition$
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Itzhak Fried, Ueli Rutishauser, Moran Cerf, and Gabriel Kreiman

Print publication date: 2014

Print ISBN-13: 9780262027205

Published to MIT Press Scholarship Online: January 2015

DOI: 10.7551/mitpress/9780262027205.001.0001

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Fifty-plus Years of Human Single Neuron Recordings: a Personal Perspective

Fifty-plus Years of Human Single Neuron Recordings: a Personal Perspective

Chapter:
(p.7) 2 Fifty-plus Years of Human Single Neuron Recordings: a Personal Perspective
Source:
Single Neuron Studies of the Human Brain
Author(s):

Itzhak Fried

Publisher:
The MIT Press
DOI:10.7551/mitpress/9780262027205.003.0002

The early history of human single neuron recording, from the first published example in 1955, is reviewed, including investigations of the pathophysiology of epilepsy and movement disorders, and during cognitive measures. The special issues related to applying the technique to studies of cognition are then discussed, including ethical considerations, choice of behaviors to be assessed, control measures, effects of subjects’ underlying disease, and the relation between information derived from these recordings and other methods for investigating the neurobiology of human cognition.

Keywords:   History of human single neuron recording, Epilepsy, Movement Disorders, Cognition, Ethics

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