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Computational Modeling Methods for Neuroscientists$
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Erik De Schutter

Print publication date: 2009

Print ISBN-13: 9780262013277

Published to MIT Press Scholarship Online: August 2013

DOI: 10.7551/mitpress/9780262013277.001.0001

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Modeling Complex Neurons

Modeling Complex Neurons

(p.259) 11 Modeling Complex Neurons
Computational Modeling Methods for Neuroscientists

Erik De Schutter

Werner Van Geit

The MIT Press

This chapter is concerned with active models of neurons with complex morphologies. It considers GENESIS and NEURON to be the two most commonly used compartmental simulator software packages. The chapter suggests that it is important to define the accuracy required in advance and also to have reliable ways to validate the model afterward in order to judge the quality of a model. It briefly addresses how to provide synaptic input to an isolated cell model, and predicts a bright future for complex neuron models that add molecular details to the classic mix of morphology and channels.

Keywords:   neurons, complex morphologies, GENESIS, NEURON, cell model, synaptic input, complex neuron models, channels

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