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Computational Modeling Methods for Neuroscientists$
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Erik De Schutter

Print publication date: 2009

Print ISBN-13: 9780262013277

Published to MIT Press Scholarship Online: August 2013

DOI: 10.7551/mitpress/9780262013277.001.0001

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Modeling Complex Neurons

Modeling Complex Neurons

Chapter:
(p.259) 11 Modeling Complex Neurons
Source:
Computational Modeling Methods for Neuroscientists
Author(s):

Erik De Schutter

Werner Van Geit

Publisher:
The MIT Press
DOI:10.7551/mitpress/9780262013277.003.0012

This chapter is concerned with active models of neurons with complex morphologies. It considers GENESIS and NEURON to be the two most commonly used compartmental simulator software packages. The chapter suggests that it is important to define the accuracy required in advance and also to have reliable ways to validate the model afterward in order to judge the quality of a model. It briefly addresses how to provide synaptic input to an isolated cell model, and predicts a bright future for complex neuron models that add molecular details to the classic mix of morphology and channels.

Keywords:   neurons, complex morphologies, GENESIS, NEURON, cell model, synaptic input, complex neuron models, channels

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