Calcium
Calcium
This chapter explores calcium dynamics in spines. It explains that spines compartmentalize calcium, and this can create input-specific synaptic plasticity. It further points out that calcium influx into spines is regulated by voltage-sensitive calcium channels, N-methyl-D-aspartate (NMDA), and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. The chapter then concludes that although spines generate input-specific calcium compartmentalization, input-specific calcium compartmentalization also occurs in neocortical interneurons without the help of spines.
Keywords: spines, calcium, N-methyl-D-aspartate, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
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