This chapter explores calcium dynamics in spines. It explains that spines compartmentalize calcium, and this can create input-specific synaptic plasticity. It further points out that calcium influx into spines is regulated by voltage-sensitive calcium channels, N-methyl-D-aspartate (NMDA), and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. The chapter then concludes that although spines generate input-specific calcium compartmentalization, input-specific calcium compartmentalization also occurs in neocortical interneurons without the help of spines.
MIT Press Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.
If you think you should have access to this title, please contact your librarian.
To troubleshoot, please check our FAQs, and if you can't find the answer there, please contact us.