This chapter presents exciting new evidence for and an interpretation of life’s deepest, most potentially profound level of chimerical union. It shows that genetic and molecular biological evidence supports the notion of the oldest organisms that merged in the formation of the modern nucleated (eukaryotic) cell, and arguably the most important for intracellular motility, was, and still is, the remnant spirochete. This chapter shows that kinetosomes, centrioles, and centrosomes display tantalizing evidence of a common origin. It hypothesizes that the undulipodium evolved from a common spirochete ancestor.