On Parkinson’s Disease
On Parkinson’s Disease
This chapter defines Parkinson’s disease for readers who are unfamiliar with this degenerative disease, which affects the brain, adversely impacting activities that are controlled by the central nervous system. The disease is a neurodegenerative disorder affecting senior citizens who are over 60 years of age and continues for a period of around 13 years with death occurring approximately at the age of 73. Its symptoms include tremors in limbs in the resting position, stiffness, slow movement, and irregularities in body postures. Parkinson’s appears mainly in the form of non-motor disorders, such as autonomic disorder, pain, mood swings, problems sleeping, and cognitive disorders. The degenerative disease occurs due to excessive secretion of pigmented dopamine in neurons in the nigra pars compacta region of the brain, along with adverse impacts of protein inclusions known as Lewy bodies.
Keywords: Parkinson’s disease, neurodegenerative disorder, cognitive dysfunction, pigmented dopamine, protein inclusions
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