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The Cognitive Neuropsychiatry of Parkinson's Disease$
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Patrick McNamara

Print publication date: 2011

Print ISBN-13: 9780262016087

Published to MIT Press Scholarship Online: August 2013

DOI: 10.7551/mitpress/9780262016087.001.0001

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Dopamine and Parkinson’s Disease Neuropsychiatry

Dopamine and Parkinson’s Disease Neuropsychiatry

(p.24) (p.25) 2 Dopamine and Parkinson’s Disease Neuropsychiatry
The Cognitive Neuropsychiatry of Parkinson's Disease

Patrick McNamara

The MIT Press

This chapter finds Parkinson’s disease (PD) to be the main cause of excessive secretion of pigmented dopamine in brain cells, which results in degenerating agentic functions and neuropsychiatric disorders. A patient suffering from PD fails to perform basic agentic functions properly due to the side effects of dopamine secretion, and to degenerating memory and neuropsychiatric disorders. Dopamine is mainly produced in three leading nuclei of the midbrain: The retrorubral area, the substantia nigra pars, and the ventral tegmental area. Many significant motor, motivational, and cognitive components are affected by excessive dopamine secretions from these three major midbrain nuclei, giving rise to neurodegenerative disorders.

Keywords:   pigmented dopamine, brain cells, dopamine secretion, midbrain nuclei, neurodegenerative disorders

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