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Nurturing the Older Brain and Mind$
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Pamela M. Greenwood and Raja Parasuraman

Print publication date: 2012

Print ISBN-13: 9780262017145

Published to MIT Press Scholarship Online: August 2013

DOI: 10.7551/mitpress/9780262017145.001.0001

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PRINTED FROM MIT PRESS SCHOLARSHIP ONLINE (www.mitpress.universitypressscholarship.com). (c) Copyright The MIT Press, 2022. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in MITSO for personal use.date: 04 July 2022

Estrogen and Other Cognition-Enhancing Drugs

Estrogen and Other Cognition-Enhancing Drugs

(p.127) 8 Estrogen and Other Cognition-Enhancing Drugs
Nurturing the Older Brain and Mind

Pamela M. Greenwood

Raja Parasuraman

The MIT Press

This chapter discusses the pros and cons of using estrogen and cognition-enhancing drugs in treating neuropsychiatric conditions, and presents health risks related to a decrease in estrogen levels in middle-age women, including Alzheimer’s disease, depression, and cognitive impairment. The use of hormone-replacement therapy for women during and after menopause, whose estrogen levels were low, was questioned following the Women’s Health Initiative report of risks and benefits of estrogen replacement. The chapter presents studies on the use of cognition-enhancing drugs by healthy, older individuals. The use of amphetamines to enhance cognition in older people is discussed along with its drawback of being addictive. The chapter discusses the positive effect of caffeine on improving cognition and its impact on the pathology of Alzheimer’s disease.

Keywords:   estrogen, cognition-enhancing drugs, neuropsychiatric conditions, hormone-replacement therapy, Alzheimer’s disease

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