Lessons from Clinical Case Studies in Research Misconduct
Lessons from Clinical Case Studies in Research Misconduct
For four cases of prolonged research misconduct over a decade or more, undetected by peer review, replication, coauthors or institutional oversight, are described. Several of these cases also involved human subjects protection violations which, if properly investigated, would have revealed the misconduct. Citation to fabricated/falsified studies continued for years and tracing harm to subjects or eventual patients rarely addressed. Charges of research misconduct can also be used to stop or slow a competitor's program of research or be used by a company whose product sales would be damaged by the research findings. Ongoing and cumulative analysis of research misconduct cases offers lessons learned.
Keywords: case analysis, continued infraction, harm to subjects and patients
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