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The Genealogy of a GenePatents, HIV/AIDS, and Race$
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Myles W. Jackson

Print publication date: 2015

Print ISBN-13: 9780262028660

Published to MIT Press Scholarship Online: September 2015

DOI: 10.7551/mitpress/9780262028660.001.0001

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PRINTED FROM MIT PRESS SCHOLARSHIP ONLINE (www.mitpress.universitypressscholarship.com). (c) Copyright The MIT Press, 2020. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in MITSO for personal use.date: 06 April 2020

The Story of the CCR5 Gene

The Story of the CCR5 Gene

Chapter:
(p.1) 1 The Story of the CCR5 Gene
Source:
The Genealogy of a Gene
Author(s):

Myles W. Jackson

Publisher:
The MIT Press
DOI:10.7551/mitpress/9780262028660.003.0001

The introductory chapter proffers an overview of the history of the CCR5 gene. It discusses the rush to patent a sequence, whose precise function was unknown at the time of the patent. It also explores how the function of the gene was elucidated by various laboratories worldwide. Finally, this chapter outlines how an important mutation, Δ32‎, confers near immunity to AIDS and what the distribution of that allele is around the globe. The distribution of this allele worldwide added to the debate about race and the genome.

Keywords:   gene patents, HIV/AIDS, race and genomics, CCR5, Δ‎32

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