The Genealogy of a Gene: Patents, HIV/AIDS, and Race
Myles W. Jackson
Abstract
This book uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied ‘genealogy’ of CCR5- intellectual property, natural selection, Big and Small Pharma, human diversity studies, personalized medicine, ancestry studies, and race and genomics, this historical study links a myriad of diverse topics. The history of CCR5 from the 1990s to the present offers a vivid illustration of how intellectual property law has changed the conduct and content of scientific knowledge, and the social, political, and ethical implications of such ... More
This book uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied ‘genealogy’ of CCR5- intellectual property, natural selection, Big and Small Pharma, human diversity studies, personalized medicine, ancestry studies, and race and genomics, this historical study links a myriad of diverse topics. The history of CCR5 from the 1990s to the present offers a vivid illustration of how intellectual property law has changed the conduct and content of scientific knowledge, and the social, political, and ethical implications of such a transformation. Because this gene codes for the HIV-co-receptor, this account explores how Big and Small Pharma alike drew upon state-of-the-art research to come up with a new form of HIV/AIDS treatment. An important mutation of the gene renders its fortunate possesses by and large immune to AIDS. Since this mutation is found in some populations with a much greater frequency than others, the gene also serves as a prime example of how molecular biology has been drawn into debates about race. Finally, this book discusses the relevance of history of science to current science policy issues.
Keywords:
gene patents,
race and genomics,
Big Pharma,
HIV/AIDS,
science and society,
CCR5 gene,
personal genomics companies,
personalized medicine/pharmacogenomics,
Maraviroc,
biocapitalism
Bibliographic Information
| Print publication date: 2015 |
Print ISBN-13: 9780262028660 |
| Published to MIT Press Scholarship Online: September 2015 |
DOI:10.7551/mitpress/9780262028660.001.0001 |
