This chapter examines McCulloch’s activities at Yale University during the 1930s, and the ways in which his work as a neurophysiologist was inseparable from his pursuits in scientific philosophy. Broadly speaking, it casts the growth of neurophysiology in the American interwar period as the result in part of efforts of the Rockefeller Foundation to rationalize scientific studies of the mind and bring the natural sciences to bear on the growing field of psychiatry. This period also witnessed increased fluidity between science and philosophy. McCulloch was transformed by both developments. His work in cerebral localization with Johannes Dusser de Barenne and his participation in Clark Hull’s seminars in on scientific foundations formed part of a unified project to generate a physiological theory of knowledge.
Keywords: Neurophysiology, Yale University, Rockefeller Foundation, Johannes G. Dusser de Barenne, cerebral localization, Institute of Human Relations, Clark L. Hull, scientific philosophy, logical empiricism
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