This Chapter looks at the role played by transmission of the archive through the body, drawing from performance studies, bioart, database aesthetics and history of science to look at what becomes of the archive in the era of genomic experimentation. Drawing on economics, the chapter establishes the role played by the archive within the digital economy showing how the archive evolved for each of the industrial revolutions that occurred since the 18th century. Additionally, the Chapter analyzes the role played by the archive in the development of smart objects within the internet of things. The case studies for this chapter include work by the Musée de la Danse; George Legrady; Natalie Bookchin; Eduardo Kac; Christine Borland; and Lynn Hershman Leeson’s Infinity Engine, in which the human being has become its own (a-)live archive, one that, through regenerative medicine, can be modified inside out.