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A New Understanding of Mental DisordersComputational Models for Dimensional Psychiatry$
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Andreas Heinz

Print publication date: 2017

Print ISBN-13: 9780262036894

Published to MIT Press Scholarship Online: May 2018

DOI: 10.7551/mitpress/9780262036894.001.0001

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PRINTED FROM MIT PRESS SCHOLARSHIP ONLINE (www.mitpress.universitypressscholarship.com). (c) Copyright The MIT Press, 2022. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in MITSO for personal use.date: 24 June 2022

Learning Mechanisms in Addictive Disorders

Learning Mechanisms in Addictive Disorders

(p.113) 8 Learning Mechanisms in Addictive Disorders
A New Understanding of Mental Disorders

Andreas Heinz

The MIT Press

Addictive disorders may best be described as attribution of salience to drug-associated cues and drug consumption at the expense of other reinforcers. Dopamine and serotonin dysfunction can contribute to these states due to drug-associated neuroadaptation and alterations in bottom-up and top-down information processing. Relevant findings are described with respect to their computational and behavioral implications.

Keywords:   Addictive disorders, Salience, Drug consumption, Drug-associated cues, Dopamine, Serotonin, Neuroadaptation

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