- Title Pages
- Preface
- Acknowledgments
-
1 Introduction -
2 Genomes as Permutations -
3 Distances between Unsigned Permutations -
4 Distances between Signed Permutations -
5 Rearrangements of Partial Orders -
6 Graph-Theoretic and Linear Algebra Formulations -
7 Generalities -
8 Distances between Arbitrary Strings -
9 Distances between Balanced Strings -
III Multichromosomal Models -
10 Paths and Cycles -
11 Cycles of a Permutation -
12 Set Systems and the Syntenic Distance -
IV Multigenomic Models -
13 Median and Halving Problems -
14 Rearrangement Phylogenies -
15 Software -
16 Open Problems -
A Graph Theory -
B Complexity Theory - [UNTITLED]
- Glossary
- Bibliography
- Index
Distances between Signed Permutations
Distances between Signed Permutations
- Chapter:
- (p.63) 4 Distances between Signed Permutations
- Source:
- Combinatorics of Genome Rearrangements
- Author(s):
Guillaume Fertin
Anthony Labarre
Irena Rusu
Eric Tannier
Steéphane Vialette
- Publisher:
- The MIT Press
Signed permutations allow the relative orientation of homologous markers to be taken into account and constitute a more biologically relevant model for genomes. Reversals, for instance, always change the strand of the reversed segment, so that the orientation of a gene inside the segment is also changed. Thus, whenever the orientation of genes is known and mutations that affect orientations are considered, it is better to use signed permutations as a model. This chapter discusses conserved interval distance; signed reversal distance; variants of sorting by reversals; combined operations; and double cut-and-joins.
Keywords: homologous markers, genomes, signed permutations, interval distance, reversal distance, double cut-and-joins
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- Title Pages
- Preface
- Acknowledgments
-
1 Introduction -
2 Genomes as Permutations -
3 Distances between Unsigned Permutations -
4 Distances between Signed Permutations -
5 Rearrangements of Partial Orders -
6 Graph-Theoretic and Linear Algebra Formulations -
7 Generalities -
8 Distances between Arbitrary Strings -
9 Distances between Balanced Strings -
III Multichromosomal Models -
10 Paths and Cycles -
11 Cycles of a Permutation -
12 Set Systems and the Syntenic Distance -
IV Multigenomic Models -
13 Median and Halving Problems -
14 Rearrangement Phylogenies -
15 Software -
16 Open Problems -
A Graph Theory -
B Complexity Theory - [UNTITLED]
- Glossary
- Bibliography
- Index