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ProtocellsBridging Nonliving and Living Matter$
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Steen Rasmussen, Mark A. Bedau, Liaohai Chen, David Deamer, David C. Krakauer, Norman H. Packard, and Peter F. Stadler

Print publication date: 2008

Print ISBN-13: 9780262182683

Published to MIT Press Scholarship Online: August 2013

DOI: 10.7551/mitpress/9780262182683.001.0001

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The Core of a Minimal Gene Set: Insights from Natural Reduced Genomes

The Core of a Minimal Gene Set: Insights from Natural Reduced Genomes

Chapter:
(p.347) 16 The Core of a Minimal Gene Set: Insights from Natural Reduced Genomes
Source:
Protocells
Author(s):

Toni Gabaldón

Rosario Gil

Juli Peretó

Amparo Latorre

Andrés Moya

Publisher:
The MIT Press
DOI:10.7551/mitpress/9780262182683.003.0016

This chapter explores the potential of peptic nucleic acids (PNAs) as prebiotic and abiotic genetic material. It first presents basic PNA chemistry and illustrates its close similarity with protein. PNA replication and catalysis are also discussed. The chapter concludes by suggesting that PNA is of eminent interest for the synthesis of protocells with the use of biological DNA- or RNA-based systems.

Keywords:   peptic nucleic acids, genetic material, PNAs, PNA replication, catalysis, protocells

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