- Title Pages
- Preface
- Acknowledgments
- Introduction
-
1 The Early History of Protocells: The Search for the Recipe of Life -
2 Experimental Approaches to Fabricating Artificial Cellular Life -
3 Semisynthetic Minimal Cells: New Advancements and Perspectives -
4 A Roadmap to Protocells -
II INTEGRATION -
5 Steps Toward a Synthetic Protocell -
6 Assembly of a Minimal Protocell -
7 Population Analysis of Liposomes with Protein Synthesis and a Cascading Genetic Network -
8 Constructive Approach to Protocells: Theory and Experiments -
9 Origin of Life and Lattice Artificial Chemistry -
10 Models of Protocell Replication -
11 Compositional Lipid Protocells: Reproduction without Polynucleotides -
12 Evolutionary Microfluidic Complementation Toward Artificial Cells -
III COMPONENTS -
13 Self-Replication and Autocatalysis -
14 Replicator Dynamics in Protocells -
15 Peptide Nucleic Acids as Prebiotic and Abiotic Genetic Material -
16 The Core of a Minimal Gene Set: Insights from Natural Reduced Genomes -
17 Parasitism and Protocells: Tragedy of the Molecular Commons -
18 Forming the Essential Template for Life: The Physics of Lipid Self-Assembly -
19 Numerical Methods for Protocell Simulations -
20 Core Metabolism as a Self-Organized System -
21 Energetics, Energy Flow, and Scaling in Life -
IV BROADER CONTEXT -
22 Gánti’s Chemoton Model and Life Criteria -
23 Viral Individuality and Limitations of the Life Concept -
24 Nonlinear Chemical Dynamics and the Origin of Life: The Inorganic-Physical Chemist Point of View -
25 Early Ancestors of Existing Cells -
26 Prebiotic Chemistry, the Primordial Replicator, and Modern Protocells -
27 Cell-like Entities: Scientific Challenges and Future Applications -
28 Social and Ethical Issues Concerning Protocells - Glossary
- About the Authors
- Index
Origin of Life and Lattice Artificial Chemistry
Origin of Life and Lattice Artificial Chemistry
- Chapter:
- (p.196) (p.197) 9 Origin of Life and Lattice Artificial Chemistry
- Source:
- Protocells
- Author(s):
Naoaki Ono
Duraid Madina
Takashi Ikegami
- Publisher:
- The MIT Press
Constructive biology aims to artificially construct a system that does not exist in nature but that has some biological features. The construction of a replicating system with compartments, for example, is essential to the study of the origins of a protocell. This chapter discusses both theory and experimental approaches to protocell production. The theoretical approach considers concepts such as the minority-controlled state, recursive production, switching, and evolvability. These concepts are related to experimental results from an in vitro replication system constructed by Tetsuya Yomo and colleagues.
Keywords: constructive biology, protocell, minority-controlled state, recursive production, switching, evolvability, replication, Tetsuya Yomo
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- Title Pages
- Preface
- Acknowledgments
- Introduction
-
1 The Early History of Protocells: The Search for the Recipe of Life -
2 Experimental Approaches to Fabricating Artificial Cellular Life -
3 Semisynthetic Minimal Cells: New Advancements and Perspectives -
4 A Roadmap to Protocells -
II INTEGRATION -
5 Steps Toward a Synthetic Protocell -
6 Assembly of a Minimal Protocell -
7 Population Analysis of Liposomes with Protein Synthesis and a Cascading Genetic Network -
8 Constructive Approach to Protocells: Theory and Experiments -
9 Origin of Life and Lattice Artificial Chemistry -
10 Models of Protocell Replication -
11 Compositional Lipid Protocells: Reproduction without Polynucleotides -
12 Evolutionary Microfluidic Complementation Toward Artificial Cells -
III COMPONENTS -
13 Self-Replication and Autocatalysis -
14 Replicator Dynamics in Protocells -
15 Peptide Nucleic Acids as Prebiotic and Abiotic Genetic Material -
16 The Core of a Minimal Gene Set: Insights from Natural Reduced Genomes -
17 Parasitism and Protocells: Tragedy of the Molecular Commons -
18 Forming the Essential Template for Life: The Physics of Lipid Self-Assembly -
19 Numerical Methods for Protocell Simulations -
20 Core Metabolism as a Self-Organized System -
21 Energetics, Energy Flow, and Scaling in Life -
IV BROADER CONTEXT -
22 Gánti’s Chemoton Model and Life Criteria -
23 Viral Individuality and Limitations of the Life Concept -
24 Nonlinear Chemical Dynamics and the Origin of Life: The Inorganic-Physical Chemist Point of View -
25 Early Ancestors of Existing Cells -
26 Prebiotic Chemistry, the Primordial Replicator, and Modern Protocells -
27 Cell-like Entities: Scientific Challenges and Future Applications -
28 Social and Ethical Issues Concerning Protocells - Glossary
- About the Authors
- Index
