Jump to ContentJump to Main Navigation
System Modeling in Cellular BiologyFrom Concepts to Nuts and Bolts$
Users without a subscription are not able to see the full content.

Zoltan Szallasi, Jorg Stelling, and Vipul Periwal

Print publication date: 2006

Print ISBN-13: 9780262195485

Published to MIT Press Scholarship Online: August 2013

DOI: 10.7551/mitpress/9780262195485.001.0001

Show Summary Details
Page of

PRINTED FROM MIT PRESS SCHOLARSHIP ONLINE (www.mitpress.universitypressscholarship.com). (c) Copyright The MIT Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in MITSO for personal use.date: 27 July 2021

Biological Data Acquisition for System Level Modeling—An Exercise in the Art of Compromise

Biological Data Acquisition for System Level Modeling—An Exercise in the Art of Compromise

Chapter:
(p.201) 10 Biological Data Acquisition for System Level Modeling—An Exercise in the Art of Compromise
Source:
System Modeling in Cellular Biology
Author(s):

Zoltan Szallasi

Publisher:
The MIT Press
DOI:10.7551/mitpress/9780262195485.003.0010

This chapter reviews biological data acquisition techniques and compares their capabilities to the data requirements of various modeling techniques and to the estimated complexity of intracellular regulatory networks. The discussions cover the estimated size and complexity of intracellular regulatory networks; classifying measurement techniques from a computational modeling perspective; low throughput, accurate measurements of gene derivative concentrations; high throughput measurements and low accuracy; detecting regulatory interactions and quantifying kinetic parameters; and population averaged versus single cell measurements.

Keywords:   biological data acquisition, intracellular regulatory networks, gene derivative concentrations, regulatory interactions, kinetic parameters

MIT Press Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs, and if you can't find the answer there, please contact us.