Using Control Theory to Study Biology*
Using Control Theory to Study Biology*
This chapter presents a framework ideally suited to an analysis of dynamic systems. Tools from control theory can be applied to elucidate the functioning of self-regulating (homeostatic) systems and to predict the effect of perturbations. It begins with an introduction to the framework of linear systems and one of the primary tools for describing their behavior: the frequency response. It then discusses how one particular type of control system, integral feedback control, plays a crucial role in both homeostasis and sensory adaptation. Next, it considers other uses of feedback mechanisms in cell signaling pathways.
Keywords: dynamic systems, control theory, self-regulating systems, frequency response, integral feedback control, homeostasis, sensory adaptation, cell signaling pathways
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