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System Modeling in Cellular BiologyFrom Concepts to Nuts and Bolts$
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Zoltan Szallasi, Jorg Stelling, and Vipul Periwal

Print publication date: 2006

Print ISBN-13: 9780262195485

Published to MIT Press Scholarship Online: August 2013

DOI: 10.7551/mitpress/9780262195485.001.0001

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PRINTED FROM MIT PRESS SCHOLARSHIP ONLINE (www.mitpress.universitypressscholarship.com). (c) Copyright The MIT Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in MITSO for personal use.date: 05 August 2021

Multilevel Modeling in Systems Biology

Multilevel Modeling in Systems Biology

From Cells to Whole Organs

Chapter:
(p.297) 14 Multilevel Modeling in Systems Biology
Source:
System Modeling in Cellular Biology
Author(s):

Denis Noble

Publisher:
The MIT Press
DOI:10.7551/mitpress/9780262195485.003.0014

This chapter discusses the philosophy of multilevel modeling and illustrates this development in the case of the heart. It covers cellular models of the heart; connecting to ion pumps and calcium cycling; connecting to ion pumps and calcium cycling; linking to biochemistry; linking to tissues and organs; coronary circulation.

Keywords:   multilevel modeling, systems biology, heart, ion pumps, calcium cycling, coronary circulation

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