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Ingenious GenesHow Gene Regulation Networks Evolve to Control Development$
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Roger Sansom

Print publication date: 2011

Print ISBN-13: 9780262195812

Published to MIT Press Scholarship Online: August 2013

DOI: 10.7551/mitpress/9780262195812.001.0001

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The Connectionist Framework for Gene Regulation

The Connectionist Framework for Gene Regulation

Chapter:
(p.69) 4 The Connectionist Framework for Gene Regulation
Source:
Ingenious Genes
Author(s):

Roger Sansom

Publisher:
The MIT Press
DOI:10.7551/mitpress/9780262195812.003.0004

This chapter discusses the adaptivity of a gene regulation network to be determined by the proportion of times that it reacts adaptively to its microenvironment. A gene regulation network is accurate to the extent that it expresses only the right genes for each microenvironment. The problem of the evolvability of gene regulation networks becomes the question of how gene regulation networks can evolve to allow such accuracy. It is proposed here that the similarity of these networks to connectionist networks is what explains their evolvability. Discussion of adaptive gene expression should boil down all the developmental and environmental complexity to the gene level, which must be done if we are to talk about the evolution of genes, but it necessarily overlooks important details of why the facts are the way they are.

Keywords:   adaptivity, gene regulation network, microenvironment, evolvability, connectionist networks, adaptive gene expression

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