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What Is Addiction?$
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Don Ross, Harold Kincaid, David Spurrett, and Peter Collins

Print publication date: 2010

Print ISBN-13: 9780262513111

Published to MIT Press Scholarship Online: August 2013

DOI: 10.7551/mitpress/9780262513111.001.0001

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PRINTED FROM MIT PRESS SCHOLARSHIP ONLINE (www.mitpress.universitypressscholarship.com). (c) Copyright The MIT Press, 2022. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in MITSO for personal use.date: 01 July 2022

Neurobiology of Pathological Gambling

Neurobiology of Pathological Gambling

(p.26) (p.27) 2 Neurobiology of Pathological Gambling
What Is Addiction?

Jennifer D. Bellegarde

Marc N. Potenza

The MIT Press

This chapter demonstrates that impulse control disorders (ICDs) and substance use disorders may share certain neurobiological features and processes, and suggests that certain neurodevelopmental features may predispose youth to developing problematic addictive behavior. It shows that the same neurodevelopmental processes which contribute to the necessary experimentation, learning, and adaptation of adolescence needed to enable children to move toward adulthood are those that render adolescents vulnerable to addiction and ICDs such as pathological gambling (PG). Neurotransmitters that promote PG are described, such as serotonin, dopamine, gamma-aminobutyric acid, glutamate, norepinephrine, opioid, neuropeptides, and monoamine oxidase. The chapter also shows that a complex interaction between genetic and environmental factors leads to PG.

Keywords:   impulse control disorders, substance use disorders, pathological gambling, addiction, neurotransmitters, neurobiological features

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