Chemoprophylaxis refers to the administration of medication to prevent disease or infection. This chapter first gives a historical overview of chemoprophylaxis in Southern Rhodesia, then turns to the problem of drug resistance and photosensitization, which is a clinical condition in which the skin's negative exposure and reaction to sunlight is heightened due to phototoxic drugs and chemicals. This photosensitivity occurs when these substances absorb sunlight (ultraviolet radiation), triggering a burning sensation, redness, and swelling. The chapter ends with a case study of chemoprophylaxis operations in Southern Rhodesia, exploring how the early promises of chemoprophylaxis ended with unforeseen complications that poisoned instead of cured animals of n'gana. The argument made is one about pollution of the most intimate kind: within the body, both of the animal and hutachiwana itself.
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